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SirT7 auto-ADP-ribosylation regulates glucose starvation response through mH2A1.
Simonet NG, Thackray JK, Vazquez BN, Ianni A, Espinosa-Alcantud M, Morales-Sanfrutos J, Hurtado-Bagès S, Sabidó E, Buschbeck M, Tischfield J, De La Torre C, Esteller M, Braun T, Olivella M, Serrano L, Vaquero A. Simonet NG, et al. Sci Adv. 2020 Jul 24;6(30):eaaz2590. doi: 10.1126/sciadv.aaz2590. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832656 Free PMC article.
Shikimic acid protects skin cells from UV-induced senescence through activation of the NAD+-dependent deacetylase SIRT1.
Martínez-Gutiérrez A, Fernández-Duran I, Marazuela-Duque A, Simonet NG, Yousef I, Martínez-Rovira I, Martínez-Hoyos J, Vaquero A. Martínez-Gutiérrez A, et al. Among authors: simonet ng. Aging (Albany NY). 2021 Apr 26;13(9):12308-12333. doi: 10.18632/aging.203010. Epub 2021 Apr 26. Aging (Albany NY). 2021. PMID: 33901008 Free PMC article.
SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair.
Vazquez BN, Thackray JK, Simonet NG, Kane-Goldsmith N, Martinez-Redondo P, Nguyen T, Bunting S, Vaquero A, Tischfield JA, Serrano L. Vazquez BN, et al. Among authors: simonet ng. EMBO J. 2016 Jul 15;35(14):1488-503. doi: 10.15252/embj.201593499. Epub 2016 May 24. EMBO J. 2016. PMID: 27225932 Free PMC article.
Sirt7 promotes adipogenesis in the mouse by inhibiting autocatalytic activation of Sirt1.
Fang J, Ianni A, Smolka C, Vakhrusheva O, Nolte H, Krüger M, Wietelmann A, Simonet NG, Adrian-Segarra JM, Vaquero A, Braun T, Bober E. Fang J, et al. Among authors: simonet ng. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8352-E8361. doi: 10.1073/pnas.1706945114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923965 Free PMC article.